Please note that this list is not exhaustive, but is intended to be used as a general guide. We advise discussing benefits and risks of all prescribed medications, including any FDA “boxed warnings,” with your doctor. Please do not start or stop a medication without first speaking with your doctor. Finally, tell your doctor about all prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other physicians.
| Trade Name | Generic Name | Route of Administration |
|---|---|---|
| Indocin | Indomethacin | Oral |
| Naprosyn | Naproxen | Oral |
| Aleve | Naproxen | Oral |
| Voltaren | Diclofenac | Oral |
| Clinoril | Sulindac | Oral |
| Feldene | Piroxicam | Oral |
| Lodine | Etodolac | Oral |
| Mobic | Meloxicam | Oral |
| Celebrex | Celecoxib | Oral |
| Motrin/Advil | Ibuprofen | Oral |
| Relafen | Nabumetone | Oral |
| Trade Name | Generic or Brand Name | Route of Administration | Additional Information |
|---|---|---|---|
| Azulfidine | Sulfasalazine | Oral | Used for peripheral arthritis in AS and related illness. |
| Rheumatrex Trexall Rosuvo | Methotrexate | Oral or subcutaneous injection | Used for peripheral arthritis in AS and related illness; steroid sparing drug for uveitis. |
| Imuran | Azathioprine | Oral | Used for peripheral arthritis in AS and related illness; used to manage colitis in SpA. |
| Otezla | Apremilast | Oral | Used for peripheral arthritis in AS and related illness. |
| Xeljanz, Xeljanz XR | Tofacitinib | Oral | Approved for ankylosing spondylitis, psoriatic arthritis |
| Rinvoq | Upadacitinib | Oral | Approved for ankylosing spondylitis, psoriatic arthritis, nr-AxSpA |
| Trade Name | Generic or Brand Name | Biosimilar Trade Name | Route of Administration | Additional Information |
|---|---|---|---|---|
| Enbrel (TNF-alpha blocker) | Etanercept | Erelzi Eticovo | Subcutaneous injection | Approved for AS, psoriatic arthritis and juvenile idiopathic arthritis. |
| Remicade (TNF-alpha blocker) | Infliximab | Inflectra Renflexis Ixifi Avsola | Intravenous infusion | Approved for AS and psoriatic arthritis. |
| Humira (TNF-alpha blocker) | Adalimumab | Amjevita Cyltezo Hyrimoz Abrilada Hadlima Hulio Yuismry Idacio Yuflyma Simlandi | Subcutaneous injection | Approved for AS, psoriatic arthritis and juvenile idiopathic arthritis. |
| Simponi (TNF-alpha blocker) | Golimumab | Subcutaneous injection | Approved for AS and psoriatic arthritis. | |
| Simponi Aria (TNF- alpha blocker) | Golimumab | Intravenous infusion | Approved for AS and psoriatic arthritis. | |
| Cimzia (TNF-alpha blocker) | Certolizumab pegol | Subcutaneous injection | Approved for AS, psoriatic arthritis and nr-axSpA | |
| Cosentyx (Interleukin 17 blocker) | Secukinumab | Subcutaneous injection | Approved for AS, nr-axSpA, psoriatic arthritis | |
| Taltz (Interleukin 17 blocker) | Ixekizumab | Subcutaneous injection | Approved for AS, nr-axSpA, psoriatic arthritis | |
| Bimzelx (Interleukin 17A and 17F blocker) | Bimekizumab-bkzx | Subcutaneous injection | Approved for AS, nr-axSpA, psoriatic arthritis | |
| Stelara (Interleukin 12 and 23 blocker) | Ustekinumab | Wezlana Pyzchiva Selarsdi Otulfi Imuldosa Yesintek Steqeyma | Intravenous infusion, then subcutaneous injection | Approved for psoriatic arthritis |
If you need assistance with the cost of your medications, visit
https://spondylitis.org/resources-support/support-resources/prescription-assistance/
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