Biosimilars

Structural Bone Changes in Spondyloarthritis: Mechanisms, Clinical Impact and Therapeutic Considerations

Spondyloarthritis (SpA) is an inflammatory disease of the spine, the peripheral joints and the entheses and shares some clinical features with rheumatoid arthritis (RA). Chronic inflammation of musculoskeletal structures leads to disease symptoms such as pain and stiffness and structural…

The Transition of Acute to Chronic Bowel Inflammation in Spondyloarthritis

That gut and joint inflammation are linked in spondyloarthritis (SpA) has been recognized for almost three decades. Intriguingly, microscopic gut inflammation, which occurs frequently in patients with SpA, is an important risk factor for clinically overt Crohn’s disease and ankylosing…

The United States National Health and Nutrition Examination Survey and the Epidemiology of Ankylosing Spondylitis

Currently available U.S. population– based data for ankylosing spondylitis (AS), spondyloarthritis and inflammatory back pain (IBP) from the nationally representative U.S. National Health and Nutrition Examination Survey (NHANES) include both NHANES I(1971–1975) and NHANES II (1976 –1980) surveys. The pelvic…

Use of Genome Wide Association Studies for Drug Repositioning

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