By Anna Lafian, DO, MS
I find it really exciting to be in the field of rheumatology nowadays. Over the past several years, I’ve found that people are tuning into the power of their everyday lifestyle choices to optimize their health and wellness. As a firm believer in lifestyle medicine, integrative medicine, and using complementary treatments alongside the powerful pharmaceuticals we have available now, I see the potential we have to make big strides in whole-person care. I am delighted when those who live with spondyloarthritis (SpA) realize that their health can indeed be influenced by factors that are within their day-to-day control.
My patients often ask, “What can I do to help improve my symptoms? What should I eat? Can I exercise with SpA?” Researching these topics on the internet or social media can inundate us with hundreds of different dietary tips, ads for new supplements, and wellness gadgets. It can feel overwhelming when we’re struggling with where to start.
For simplicity, immune wellness (and truly, wellness in general) can be classified into five main pillars: 1) Diet, 2) Exercise, 3) Stress management, 4) Sleep, 5) Reducing exposure to environmental toxins.
Diet
Hippocrates once said, “All disease begins in the gut.” There is no question that the gut microbiome—the bacteria, yeast, and other microbes that live in our intestines—plays a role in SpA. Studies have shown that rats with the HLA-B27 gene who were raised in a germ-free environment did not develop arthritis; however, when certain bacteria were re-introduced, inflammation emerged in the gut and joints.1,2 Over the past decade or so, with advances in genome sequencing techniques, researchers have been able to look more closely at the intestinal metagenome (the genetic material present in the gut) and have come to understand that those with SpA have a different gut microbial composition than the general population.3
Diet plays a key role in the makeup of the microbiome as it affects the kinds of microbes that can live and grow in the gut. In a 2021 study published in the journal Gut, researchers found a link between the consumption of processed and animal-derived foods, and intestinal bacteria implicated in driving inflammation. The opposite was found for plant-based foods and fish, which were positively associated with short-chain fatty acid (SCFA) production and efficient metabolism. SCFAs improve gut health in a number of ways, from maintaining the integrity of the intestinal barrier to protecting against inflammation.
Healthy diets enriched with fruits, vegetables, legumes, and nuts, that feature a higher intake of plant-based foods than animal-based foods—and that minimize alcohol and sugar—have the potential to prevent intestinal inflammatory processes.4
What constitutes “healthy” nutrition? Here are a few pointers I usually give my patients:
Exercise
A large literature review published in 2020 found that exercise significantly decreased pain scores in patients with ankylosing spondylitis (AS) as measured by a visual analogue scale, and significantly improved fatigue.5 In addition, the benefits of exercise for those with SpA include improved mobility and range of motion, better posture, higher quality sleep, reduced stiffness, enhanced muscle strength, and greater lung capacity.
Studies overwhelmingly show that regular physical activity promotes better functioning in SpA. Stretching, strengthening, cardiovascular, and balance exercises are key components in an effective movement program for SpA.6 Yoga, pilates, and Tai Chi, modified to suit individual mobility levels, are good options that cover many different categories of exercise. No matter what kind of exercise you do, consistency is key. Find something you enjoy doing, start slowly, and stick to a routine.
Talk to your doctor before starting a new exercise regimen—and if a particular exercise hurts, stop doing it. Physical therapists can help tailor an exercise routine to your abilities and needs. In patients who have a lot of pain, I encourage gentle exercises like Tai Chi and aquatherapy (physical therapy in a pool).
Since SpA may affect the ribcage over time, which can cause decreased mobility in the chest, I am a huge advocate for daily use of an incentive spirometer, a device that encourages you to breathe more deeply (you can find one on Amazon). Lung capacity has a direct impact on overall wellbeing and longevity.
You may experience the most pain and stiffness after a long stretch of inactivity (such as in the morning upon awakening, or after sitting for a long while). So here’s an actionable and easy tip you can follow during the day: Get up every hour at the 55-minute mark and take a five-minute break to walk and stretch. This is especially helpful if your job consists of sitting at a desk for eight hours a day.
Sleep
Sleep is a vital component of maintaining a healthy immune system. Research has shown that sleep affects a wide variety of immune functions, including the numbers of specific leukocyte subsets in circulating blood, the cell-specific production of cytokines, and other immune cell processes.7 We also know that sleep deprivation drives inflammatory processes, as opposed to healthy sleep, which helps the body repair itself.8
Unfortunately, sleep is often disrupted for those with SpA. A number of studies have demonstrated poorer sleep quality in SpA patients. One such study found significant differences between SpA patients and the general population in terms of subjective sleep quality, sleep duration, sleep disturbances, and other factors. Those with more severe disease activity naturally experienced lower quality sleep.9
The basic rules of proper sleep hygiene are as follows:
Stress Management
Stressors are all around us on a daily basis. It is inevitable that we experience some amount of stress. While acute, short-term stress is not particularly worrisome, chronic, long-term stress can wreak havoc on our health and immune system. It is well-documented that stress increases pro-inflammatory cytokines in our bodies, promoting systemic inflammation.
With that said, it is possible to mitigate life’s stressors by practicing stress management and reduction techniques. There are many options available nowadays and I hope you will find a stress management practice that speaks to you. Here are a few examples:
Avoidance of Environmental Toxins
While this topic could be an entire article on its own, here I’ll note just a few key points I tell my patients:
I hope I’ve given you the encouragement to realize there are countless ways you can modify your lifestyle to optimize your pillars of immune wellness.
References:
Anna Lafian, DO, MS is board-certified in internal medicine and rheumatology. She is an integrative rheumatologist who believes in the power of Western medicine combined with evidence-based complementary and alternative modalities to achieve immune strength. She is a firm believer in giving her patients the education and tools needed to understand their disease process and treatment options. She practices in Glendale, CA at The Healing Rheum.
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